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1

Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the α or β catalytic subunit

Brian A. Perrino, Andrew J. Wilson, Patricia Ellison, Lucie H. Clapp

Journal:

Year:

2002

Language:

english

File:

PDF, 323 KB

english, 2002

2

Dual regulation of M current in gastric smooth muscle cells: β-adrenergic-muscarinic antagonism

Stephen M. Sims, Lucie H. Clapp, John V. Walsh, Joshua J. Singer

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1990

Language:

english

File:

PDF, 1.49 MB

english, 1990

3

Substance P, like acetylcholine, augments one type of Ca2+current in isolated smooth muscle cells

Lucie H. Clapp, Michel B. Vivaudou, Joshua J. Singer, John V. Walsh

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1989

Language:

english

File:

PDF, 285 KB

english, 1989

4

Functional Expression of Inward Rectifier Potassium Channels in Cultured Human Pulmonary Smooth Muscle Cells: Evidence for a Major Role of Kir2.4 Subunits

Brian P. Tennant, Yi Cui, Andrew Tinker, Lucie H. Clapp

Journal:

Journal of Membrane Biology

Year:

2006

Language:

english

File:

PDF, 1.69 MB

english, 2006

5

Different calcium mobilisation pathways underlie the changes in vascular reactivity to norepinephrine and vasopressin in septic shock

Lucinda Barrett, Valerie Taylor, Lucie Clapp, Mervyn Singer

Journal:

Journal of Infection

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

6

Vasopressin-related alterations of sodium reabsorption in the loop of Henle

Antoniou, Lucy D, Burke, Thomas J, Robinson, Roscoe R, Clapp, James R

Journal:

Kidney International

Year:

1973

Language:

english

File:

PDF, 684 KB

english, 1973

7

The large-conductance Ca2+-activated K+ channel is essential for innate immunity

Ahluwalia, Jatinder, Tinker, Andrew, Clapp, Lucie H., Duchen, Michael R., Abramov, Andrey Y., Pope, Simon, Nobles, Muriel, Segal, Anthony W.

Journal:

Year:

2004

Language:

english

File:

PDF, 2.23 MB

english, 2004

8

The large-conductance Ca2+-activated K+ channel is essential for innate immunity

Ahluwalia, Jatinder, Tinker, Andrew, Clapp, Lucie H., Duchen, Michael R., Abramov, Andrey Y., Pope, Simon, Nobles, Muriel, Segal, Anthony W.

Journal:

Year:

2010

Language:

english

File:

PDF, 34 KB

english, 2010

9

Effects of the adenylyl cyclase inhibitor SQ22536 on iloprost-induced vasorelaxation and cyclic AMP elevation in isolated guinea-pig aorta

Sally Turcato, Lucie H Clapp

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 219 KB

english, 1999

10

Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A

Yi Cui, Andrew Tinker, Lucie H Clapp

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 197 KB

english, 2003

11

The pore-forming subunit of the KATP channel is an important molecular target for LPS-induced vascular hyporeactivity in vitro

Alastair J O'Brien, Gita Thakur, James F Buckley, Mervyn Singer, Lucie H Clapp

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 274 KB

english, 2005

12

Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: Treprostinil is a potent DP1 and EP2 agonist

Brendan J. Whittle, Adam M. Silverstein, David M. Mottola, Lucie H. Clapp

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 392 KB

english, 2012

13

Role of prostanoid IP and EP receptors in mediating vasorelaxant responses to PGI2 analogues in rat tail artery: Evidence for Gi/o modulation via EP3 receptors

Nelson N. Orie, Lucie H. Clapp

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 826 KB

english, 2011

14

Evidence that Ca2+-activated K+ channels play a major role in mediating the vascular effects of iloprost and cicaprost

Lucie H Clapp, Sally Turcato, Sharon Hall, Mohjir Baloch

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 200 KB

english, 1998

15

Abnormal Activation of K+Channels Underlies Relaxation to Bacterial Lipopolysaccharide in Rat Aorta

Sharon Hall, Sally Turcato, Lucie Clapp

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 93 KB

english, 1996

16

Both membrane stretch and fatty acids directly activate large conductance Ca2+-activated K+ channels in vascular smooth muscle cells

Michael T. Kirber, Richard W. Ordway, Lucie H. Clapp, John V. Walsh Jr., Joshua J. Singer

Journal:

Year:

1992

Language:

english

File:

PDF, 596 KB

english, 1992

17

IP receptor-dependent activation of PPARγ by stable prostacyclin analogues

Emilia Falcetti, David M. Flavell, Bart Staels, Andrew Tinker, Sheila. G. Haworth, Lucie H. Clapp

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 174 KB

english, 2007

18

Terlipressin for norepinephrine-resistant septic shock

Alastair O'Brien, Lucie Clapp, Mervyn Singer

Journal:

Year:

2002

Language:

english

File:

PDF, 61 KB

english, 2002

19

Reversal of life-threatening, drug-related potassium-channel syndrome by glibenclamide

Mervyn Singer, Flaminia Coluzzi, Alastair O'Brien, Lucie H Clapp

Journal:

Year:

2005

Language:

english

File:

PDF, 69 KB

english, 2005

20

Neurotransmitter Regulation of Ionic Channels in Freshly Dissociated Smooth Muscle Cells

STEPHEN M. SIMS, MICHEL B. VIVAUDOU, LUCIE H. CLAPP, NANCY L. LASSIGNAL, JOHN V. WALSH JR., JOSHUA J. SINGER

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1.31 MB

english, 1988

21

Counteracting effects of treprostinil and endothelin (ET-1) receptor antagonists (ETRAs) on endothelin-1, ETB receptor and ECE-1 levels in pulmonary smooth muscle cells (PASMCs) derived from patients with pulmonary arterial hypertension (PAH)

Patel, Jigisha, Hall, Susan, Clapp, Lucie

Journal:

Year:

2013

Language:

english

File:

PDF, 55 KB

english, 2013

22

Acetylcholine Increases Voltage-Activated Ca2+Current in Freshly Dissociated Smooth Muscle Cells

Lucie H. Clapp, Michel B. Vivaudou, John V. Walsh and Joshua J. Singer

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 906 KB

english, 1987

23

A comparative study of PGI2 mimetics used clinically on the vasorelaxation of human pulmonary arteries and veins, role of the DP-receptor

Benyahia, Chabha, Boukais, Kamel, Gomez, Ingrid, Silverstein, Adam, Clapp, Lucie, Fabre, Aurélie, Danel, Claire, Leséche, Guy, Longrois, Dan, Norel, Xavier

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2013

Language:

english

File:

PDF, 906 KB

english, 2013

24

Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension

Falcetti, Emilia, Hall, Susan M., Phillips, Peter G., Patel, Jigisha, Morrell, Nicholas W., Haworth, Sheila G., Clapp, Lucie H.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 1.79 MB

english, 2010

25

The mechanistic basis of prostacyclin and its stable analogues in pulmonary arterial hypertension: Role of membrane versus nuclear receptors

Clapp, Lucie H., Gurung, Rijan

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

26

Endothelium-derived hyperpolarization factor (EDHF) is up-regulated in a pig model of acute liver failure

Ekse, Sveinung, Clapp, Lucie H., Revhaug, Arthur, Marius Ytrebø, Lars

Journal:

Scandinavian Journal of Gastroenterology

Year:

2007

Language:

english

File:

PDF, 185 KB

english, 2007

27

Differential Effects of Stable Prostacyclin Analogs on Smooth Muscle Proliferation and Cyclic AMP Generation in Human Pulmonary Artery

Clapp, Lucie H., Finney, Paul, Turcato, Sally, Tran, Sandy, Rubin, Lewis J., Tinker, Andrew

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2002

Language:

english

File:

PDF, 113 KB

english, 2002

28

The Molecular Composition of K ATP Channels in Human Pulmonary Artery Smooth Muscle Cells and Their Modulation by Growth

Cui, Yi, Tran, Sandy, Tinker, Andrew, Clapp, Lucie H.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2002

Language:

english

File:

PDF, 200 KB

english, 2002

29

Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents

Benyahia, Chabha, Ozen, Gulsev, Orie, Nelson, Ledwozyw, Agatha, Louedec, Liliane, Li, Fangfang, Senbel, Amira M., Silverstein, Adam, Danel, Claire, Longrois, Dan, Clapp, Lucie H., Norel, Xavier, Topal

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2015

Language:

english

File:

PDF, 795 KB

english, 2015

30

Assembly Limits the Pharmacological Complexity of ATP-sensitive Potassium Channels

Giblin, Jonathan P., Cui, Yi, Clapp, Lucie H., Tinker, Andrew

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 830 KB

english, 2002

31

Letters to the Editor

John M. Carroll, Dorothy Floerchinger, Herb H. Zwemke, T. Eugene Barrows, Joel Overholser, Lucie Clapp Hagens, John Byrne Cooke, Paul Shea, Gerald Davidson and Dano Boboth

Journal:

Montana: The Magazine of Western History

Year:

1987

Language:

english

File:

PDF, 337 KB

english, 1987

32

Vasopressin: Mechanisms of action on the vasculature in health and in septic shock

Barrett, Lucinda K., Singer, Mervyn, Clapp, Lucie H.

Journal:

Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 594 KB

english, 2007

33

Inhibition of vascular adenosine triphosphate-sensitive potassium channels by sympathetic tone during sepsis

Chan, Yi-Ling, Orie, Nelson N., Dyson, Alex, Taylor, Valerie, Stidwill, Raymond P., Clapp, Lucie H., Singer, Mervyn

Journal:

Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

34

BK Large Conductance Ca2+-Activated K+ Channel-Deficient Mice are not Resistant to Hypotension and Display Reduced Survival Benefit Following Polymicrobial Sepsis

O'Brien, Alastair J., Terala, Deepti, Orie, Nelson N., Davies, Nathan A., Zolfaghari, Parjam, Singer, Mervyn, Clapp, Lucie H.

Journal:

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

35

Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis*

Barrett, Lucinda K., Orie, Nelson N., Taylor, Valerie, Stidwill, Raymond P., Clapp, Lucie H., Singer, Mervyn

Journal:

Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 501 KB

english, 2007

36

VARIABLE EFFECTS OF INHIBITING iNOS AND CLOSING THE VASCULAR ATP-SENSITIVE POTASSIUM CHANNEL (VIA ITS PORE-FORMING AND SULFONYLUREA RECEPTOR SUBUNITS) IN ENDOTOXIC SHOCK

O'Brien, Alastair, Stidwill, Raymond P., Clapp, Lucie H., Singer, Mervyn

Journal:

Year:

2009

Language:

english

File:

PDF, 1.43 MB

english, 2009

37

Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heart

Holmboe, Sarah, Andersen, Asger, Jensen, Rebekka V., Kimose, Hans Henrik, Ilkjær, Lars B., Shen, Lei, Clapp, Lucie H., Nielsen-Kudsk, Jens Erik

Journal:

Pulmonary Circulation

Year:

2017

Language:

english

File:

PDF, 449 KB

english, 2017

38

Inotropic Effects of Prostacyclins on the Right Ventricle Are Abolished in Isolated Rat Hearts With Right-Ventricular Hypertrophy and Failure

Holmboe, Sarah, Andersen, Asger, Johnsen, Jacob, Nielsen, Jan Møller, Nørregaard, Rikke, Bøtker, Hans Erik, Clapp, Lucie H., Nielsen-Kudsk, Jens Erik

Journal:

Journal of Cardiovascular Pharmacology

Year:

2017

Language:

english

File:

PDF, 1018 KB

english, 2017

39

Prostanoid EP2 Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells

Patel, Jigisha, Shen, Lei, Hall, Susan, Benyahia, Chabha, Norel, Xavier, McAnulty, Robin, Moledina, Shahin, Silverstein, Adam, Whittle, Brendan, Clapp, Lucie

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 3.21 MB

english, 2018

40

Attenuated vascular responsiveness to K+ channel openers in diabetes mellitus: the differential role of reactive oxygen species

Owu, Daniel U., Orie, Nelson N., Nwokocha, Chukwuemeka R., Muzyamba, Morris, Clapp, Lucie H., Osim, Eme E.

Journal:

General Physiology and Biophysics

Year:

2013

Language:

english

File:

PDF, 441 KB

english, 2013

41

RALINEPAG REDUCES PULMONARY VASCULAR RESISTANCE (PVR) IN A PHASE 2 STUDY CONFIRMING PRECLINICAL FINDINGS ON PROSTACYCLIN (IP) RECEPTORS IN HUMAN TISSUES

PRESTON, IOANA, SHEN, LEI, PATEL, JIGISHA, SOOD, NAMITA, TORRES, FERNANDO, CADARET, LINDA, ADAMS, JOHN, CLAPP, LUCIE

Journal:

Year:

2018

Language:

english

File:

PDF, 96 KB

english, 2018

42

Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension

Shen, Lei, Patel, Jigisha A., Norel, Xavier, Moledina, Shahin, Whittle, Brendan J., von Kessler, Kirby, Sista, Prakash, Clapp, Lucie H.

Journal:

Biochemical Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.29 MB

english, 2019

43

Exploring the enzymatic degradation of poly(glycerol adipate)

Swainson, Sadie M.E., Taresco, Vincenzo, Pearce, Amanda K., Clapp, Lucie H., Ager, Barry, McAllister, Mark, Bosquillon, Cynthia, Garnett, Martin C.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2019

Language:

english

File:

PDF, 1.65 MB

english, 2019

44

Selexipag in the management of pulmonary arterial hypertension: an update

Coghlan, J Gerry, Picken, Christina, Clapp, Lucie H.

Journal:

Drug Healthcare and Patient Safety

Year:

2019

Language:

english

File:

PDF, 317 KB

english, 2019

45

Bronchodilation induced by PGE 2 is impaired in Group‐III pulmonary hypertension

Ozen, Gulsev, Benyahia, Chabha, Mani, Salma, Boukais, Kamel, Silverstein, Adam M., Bayles, Richard, Nelsen, Andrew C., Castier, Yves, Danel, Claire, Mal, Hervé, Clapp, Lucie H., Longrois, Dan, Norel,

Journal:

British Journal of Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.22 MB

english, 2019

46

Altered cyclooxygenase-1 and enhanced thromboxane receptor activities underlie attenuated endothelial dilatory capacity of omental arteries in obesity

Raees, Asmaa, Backhamis, Aysha, Mohamed-Ali, Vidya, Bashah, Moataz, Al-Jaber, Mashael, Abraham, David, Clapp, Lucie H., Orie, Nelson N.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.40 MB

english, 2019

47

Synthetic routes to treprostinil N-acyl methylsulfonamide

Picken, Christina, Laing, Peter, Shen, Lei, Clapp, Lucie H., Brocchini, Steve

Journal:

Tetrahedron Letters

Year:

2019

File:

PDF, 539 KB

2019

48

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] C62. EXPERIMENTAL MODELS IN PULMONARY HYPERTENSION II - Inhibition Of Endothelin-1 Levels By Treprostinil Is Counteracted By Bostentan And Ambrisentan In Smooth Muscle Cells Derived From Patients With Pulmonary Arterial Hypertension

Patel, Jigisha, Hall, Susan M., Clapp, Lucie H.

Year:

2012

File:

PDF, 18 KB

2012

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